منابع مشابه
Intraocular cilia in retinal detachment.
Fig. 1a. Appearance at presentation. Visual acuity 6/120 in the right eye. Fig. 1b. Clinical picture showing right proptosis 5 days after presentation. Fig. 1c. B-scan 5 days after presentation showing vitreous opacities and retinal detachment. Fig. 1d. Histopathological examination. Cross section of the intraocular foreign material revealing hair material (H&E, original magnifi cation x400). F...
متن کاملPrimary cilia signaling mediates intraocular pressure sensation.
Lowe syndrome is a rare X-linked congenital disease that presents with congenital cataracts and glaucoma, as well as renal and cerebral dysfunction. OCRL, an inositol polyphosphate 5-phosphatase, is mutated in Lowe syndrome. We previously showed that OCRL is involved in vesicular trafficking to the primary cilium. Primary cilia are sensory organelles on the surface of eukaryotic cells that medi...
متن کاملPrimary cilia
The primary cilium was first so named by Sergei Sorokin in 1968.[1] Since the discovery of primary cilium in 1898 by Zimmerman, three major hypotheses for their function have been put forth. The first is that primary cilia are vestigial organelles inherited from an ancestor whose cells had motile cilia and now are of no purpose in multicellular organisms. The second is that they are involved in...
متن کاملCilia graft.
Numerous aetiological factors can be involved in loss of eyelid substance and ideally, wherever possible, such deficits are closed by primary anastomosis. However, in the presence of extensive trauma, tumour formation, or congenital anomaly, a number of reconstructive techniques may have to be employed. These are outlined elsewhere (Smith, I959; Smith and English, 1970), but briefly to recapitu...
متن کاملCilia signaling
Cilia signaling I t takes well-built cilia to send developmental signals on their way, show Tamara Caspary, Kathryn Anderson (Sloan-Kettering Institute, New York, NY), and Christine Larkins (Emory University, Atlanta, GA). Cilia that lack the correct internal architecture fail to transduce Hedgehog (Hh) signals correctly. Hh signaling is particularly well-characterized in the developing nervous...
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ژورنال
عنوان ژورنال: Indian Journal of Ophthalmology
سال: 2018
ISSN: 0301-4738
DOI: 10.4103/ijo.ijo_487_18